PAFAH1B3 and MEI4

Data Source:
BioGRID (two hybrid)

		PAFAH1B3	MEI4
Description		platelet activating factor acetylhydrolase 1b catalytic subunit 3	meiotic double-stranded break formation protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Membrane	Lateral Element
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Spermatogenesis Nervous System Development Brain Development Lipid Catabolic Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis
Pathways		COPI-independent Golgi-to-ER retrograde traffic
Drugs		(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
Diseases
GWAS			Brain volume in infants (white matter) ( 28763065) Cadmium levels ( 26025379) Macular thickness ( 30535121)
Interacting Genes		36 interacting genes: BRD7 CCDC90B CHMP7 COPS6 CRMP1 DDX24 ECH1 EEF1A1 ERG28 GAPDH GBP2 GDF9 HSPH1 IGSF21 LNX1 LRIF1 MED31 MEI4 NIF3L1 PAFAH1B1 PAFAH1B2 PICK1 PLEKHM1 RBM48 SDCBP2 SETDB1 SUMO4 TERF1 TERF2IP TLE1 TP53 TUBB2A UNC119 XRCC6 ZBTB16 ZHX1	36 interacting genes: AFMID BAG4 C19orf25 C1orf109 CABP5 CDKN2D CHAF1A CPNE2 CST9L CTTNBP2 DNTT EIF5A FKBP6 GRB2 HSD3B7 IQGAP1 LGALS14 MACO1 METTL21A MLX MTMR9 MYO5B NGB NME7 OSGIN1 PAFAH1B3 PHYHIPL PLEKHA4 POLR1C R3HDM2 TRAPPC2L TRIM59 TSEN15 TSSK3 USHBP1 VPS26C
Entrez ID		5050	101928601
HPRD ID		04354
Ensembl ID		ENSG00000079462	ENSG00000269964
Uniprot IDs		A0A024R0L6 Q15102	A8MW99
PDB IDs
Enriched GO Terms of Interacting Partners?
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