MEI4 and CTTNBP2

Data Source:
BioGRID (two hybrid)

		MEI4	CTTNBP2
Description		meiotic double-stranded break formation protein 4	cortactin binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lateral Element	Cell Cortex Synaptic Vesicle Dendritic Spine Postsynaptic Actin Cytoskeleton Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding SH3 Domain Binding
	Biological Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis	Brain Development Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Pathways
Drugs
Diseases
GWAS		Brain volume in infants (white matter) ( 28763065) Cadmium levels ( 26025379) Macular thickness ( 30535121)	Brain morphology (MOSTest) ( 32665545) General factor of neuroticism ( 30867560) Glaucoma ( 31959993 30054594) Glaucoma (primary open-angle) ( 29891935) Idiopathic osteonecrosis of the femoral head ( 28000841) Intraocular pressure ( 29617998 29785010 31959993 30054594) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Subcortical volume (MOSTest) ( 32665545) Triglyceride levels ( 30108155) Type 2 diabetes ( 30054458 30297969) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		36 interacting genes: AFMID BAG4 C19orf25 C1orf109 CABP5 CDKN2D CHAF1A CPNE2 CST9L CTTNBP2 DNTT EIF5A FKBP6 GRB2 HSD3B7 IQGAP1 LGALS14 MACO1 METTL21A MLX MTMR9 MYO5B NGB NME7 OSGIN1 PAFAH1B3 PHYHIPL PLEKHA4 POLR1C R3HDM2 TRAPPC2L TRIM59 TSEN15 TSSK3 USHBP1 VPS26C	10 interacting genes: APPL1 ARNTL2 CTTN FAM86C1P HSF2BP INCA1 KRT14 MAGEA11 MEI4 PKNOX2
Entrez ID		101928601	83992
HPRD ID			09890
Ensembl ID		ENSG00000269964	ENSG00000077063
Uniprot IDs		A8MW99	Q20BG9 Q8WZ74
PDB IDs
Enriched GO Terms of Interacting Partners?
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