MEI4 and PAFAH1B3

Data Source:
BioGRID (two hybrid)

		MEI4	PAFAH1B3
Description		meiotic double-stranded break formation protein 4	platelet activating factor acetylhydrolase 1b catalytic subunit 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lateral Element	Cytoplasm Cytosol 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Membrane
	Molecular Function	Protein Binding	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity
	Biological Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis	Lipid Metabolic Process Spermatogenesis Nervous System Development Brain Development Lipid Catabolic Process
Pathways			COPI-independent Golgi-to-ER retrograde traffic
Drugs			(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
Diseases
GWAS		Brain volume in infants (white matter) ( 28763065) Cadmium levels ( 26025379) Macular thickness ( 30535121)
Interacting Genes		36 interacting genes: AFMID BAG4 C19orf25 C1orf109 CABP5 CDKN2D CHAF1A CPNE2 CST9L CTTNBP2 DNTT EIF5A FKBP6 GRB2 HSD3B7 IQGAP1 LGALS14 MACO1 METTL21A MLX MTMR9 MYO5B NGB NME7 OSGIN1 PAFAH1B3 PHYHIPL PLEKHA4 POLR1C R3HDM2 TRAPPC2L TRIM59 TSEN15 TSSK3 USHBP1 VPS26C	36 interacting genes: BRD7 CCDC90B CHMP7 COPS6 CRMP1 DDX24 ECH1 EEF1A1 ERG28 GAPDH GBP2 GDF9 HSPH1 IGSF21 LNX1 LRIF1 MED31 MEI4 NIF3L1 PAFAH1B1 PAFAH1B2 PICK1 PLEKHM1 RBM48 SDCBP2 SETDB1 SUMO4 TERF1 TERF2IP TLE1 TP53 TUBB2A UNC119 XRCC6 ZBTB16 ZHX1
Entrez ID		101928601	5050
HPRD ID			04354
Ensembl ID		ENSG00000269964	ENSG00000079462
Uniprot IDs		A8MW99	A0A024R0L6 Q15102
PDB IDs
Enriched GO Terms of Interacting Partners?
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