PAFAH1B3 and ECH1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PAFAH1B3	ECH1
Description		platelet activating factor acetylhydrolase 1b catalytic subunit 3	enoyl-CoA hydratase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Membrane	Mitochondrion Peroxisome Peroxisomal Matrix Cytosol Membrane Extracellular Exosome
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity	Protein Binding Delta3,5-delta2,4-dienoyl-CoA Isomerase Activity
	Biological Process	Lipid Metabolic Process Spermatogenesis Nervous System Development Brain Development Lipid Catabolic Process	Protein Targeting To Peroxisome Fatty Acid Beta-oxidation
Pathways		COPI-independent Golgi-to-ER retrograde traffic	Peroxisomal protein import Peroxisomal protein import
Drugs		(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
Diseases
GWAS			Blood protein levels ( 30072576) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		36 interacting genes: BRD7 CCDC90B CHMP7 COPS6 CRMP1 DDX24 ECH1 EEF1A1 ERG28 GAPDH GBP2 GDF9 HSPH1 IGSF21 LNX1 LRIF1 MED31 MEI4 NIF3L1 PAFAH1B1 PAFAH1B2 PICK1 PLEKHM1 RBM48 SDCBP2 SETDB1 SUMO4 TERF1 TERF2IP TLE1 TP53 TUBB2A UNC119 XRCC6 ZBTB16 ZHX1	11 interacting genes: APP CSTF2 EEF1D EEF1G FAM9B HTT PAFAH1B3 SERPINB9 STAT3 TIMP1 TLR10
Entrez ID		5050	1891
HPRD ID		04354	02825
Ensembl ID		ENSG00000079462	ENSG00000104823
Uniprot IDs		A0A024R0L6 Q15102	A0A384MR44 Q13011
PDB IDs			2VRE
Enriched GO Terms of Interacting Partners?
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