NKG7 and PEX12

Data Source:
BioGRID (two hybrid)

		NKG7	PEX12
Description		natural killer cell granule protein 7	peroxisomal biogenesis factor 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Peroxisomal Importomer Complex
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding
	Biological Process		Protein Monoubiquitination Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination
Pathways			E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import
Drugs
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		45 interacting genes: AGTRAP AMIGO1 AQP6 ARL13B ATP6AP2 BAMBI CD53 CD79A CLDN7 CLEC2D CLEC4E CLSTN3 CREB3 EBP EDA2R ERGIC3 FAM210B FFAR2 FNDC9 GJA5 GORAB GPX8 ISLR2 KLRC1 LHFPL5 LMNA MFSD6 MGST3 MS4A3 MSR1 MUC1 OPRK1 PEX12 RAMP1 RNF24 SLC18A2 SLC30A8 STOM STX1A TLCD4 TMEM106C TMEM130 TMEM139 TMEM80 TMEM88	36 interacting genes: ACSL5 ADIPOQ BNIP2 BTN2A2 C5orf46 CLDN10 COL8A2 CXCL16 CYBC1 DNAJC30 ERMP1 FA2H FKBP8 FXYD6 GJB2 IER3IP1 MARCHF2 MGLL NKG7 NRM PEX10 PEX19 PEX5 PNLIPRP1 PTPN9 RBFA SEC22A SEC61G SMCO4 SRGN STX8 THSD7B TMEM11 TMEM222 TREX1 TTPA
Entrez ID		4818	5193
HPRD ID		16188	03455
Ensembl ID		ENSG00000105374	ENSG00000108733
Uniprot IDs		Q16617	O00623
PDB IDs
Enriched GO Terms of Interacting Partners?
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