GET3 and RHEX

Data Source:
BioGRID (two hybrid)

		GET3	RHEX
Description		guided entry of tail-anchored proteins factor 3, ATPase	regulator of hemoglobinization and erythroid cell expansion
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding	Erythropoietin Receptor Binding Protein Binding
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane	Cellular Response To Erythropoietin Erythropoietin-mediated Signaling Pathway Erythrocyte Maturation Positive Regulation Of Erythrocyte Differentiation
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		ATP
Diseases
GWAS
Interacting Genes		41 interacting genes: AGR2 APLN ASPH CACNA1A CAMLG CREB3L4 EMSY FAM209A FKBP7 GET4 GOLM1 GPX7 GPX8 HILPDA IGFBP6 KCNE4 KCNE5 LDLRAD4 PDIA6 PEX14 PFDN1 PGRMC1 PGRMC2 PRB3 PRR4 RHEX SEC61A1 SEC61B SMIM19 SPP1 STATH STX5 SYPL2 TK1 TMEM154 TMEM51 TMX1 TTR VAMP2 VWC2 WFDC3	7 interacting genes: GAD2 GET3 PBX3 RBFA SH3GL1 SH3GLB1 SNX1
Entrez ID		439	440712
HPRD ID		03555	17400
Ensembl ID		ENSG00000198356	ENSG00000263961
Uniprot IDs		O43681	Q6ZWK4
PDB IDs		6SO5
Enriched GO Terms of Interacting Partners?
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