GET3 and SMIM19

		GET3	SMIM19
Description		guided entry of tail-anchored proteins factor 3, ATPase	small integral membrane protein 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome	Integral Component Of Membrane
	Molecular Function	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding	Protein Binding
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		ATP
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Gut microbiota (functional units) ( 27694959) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin concentration ( 28453575)
Interacting Genes		41 interacting genes: AGR2 APLN ASPH CACNA1A CAMLG CREB3L4 EMSY FAM209A FKBP7 GET4 GOLM1 GPX7 GPX8 HILPDA IGFBP6 KCNE4 KCNE5 LDLRAD4 PDIA6 PEX14 PFDN1 PGRMC1 PGRMC2 PRB3 PRR4 RHEX SEC61A1 SEC61B SMIM19 SPP1 STATH STX5 SYPL2 TK1 TMEM154 TMEM51 TMX1 TTR VAMP2 VWC2 WFDC3	5 interacting genes: ASPH GET3 JAGN1 UBQLN1 UBQLN2
Entrez ID		439	114926
HPRD ID		03555	14005
Ensembl ID		ENSG00000198356	ENSG00000176209
Uniprot IDs		O43681	Q96E16
PDB IDs		6SO5
Enriched GO Terms of Interacting Partners?
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