C5orf46 and PEX12

Data Source:
BioGRID (two hybrid)

		C5orf46	PEX12
Description		chromosome 5 open reading frame 46	peroxisomal biogenesis factor 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Exosome	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Peroxisomal Importomer Complex
	Molecular Function	Molecular_function Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding
	Biological Process	Biological_process	Protein Monoubiquitination Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination
Pathways			E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import
Drugs
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Alcoholic chronic pancreatitis ( 28754779)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		12 interacting genes: AQP6 EBP FAM210B LHFPL5 PEX12 RUSF1 SGTA SGTB SLC30A2 TBXA2R TIMMDC1 TMEM80	36 interacting genes: ACSL5 ADIPOQ BNIP2 BTN2A2 C5orf46 CLDN10 COL8A2 CXCL16 CYBC1 DNAJC30 ERMP1 FA2H FKBP8 FXYD6 GJB2 IER3IP1 MARCHF2 MGLL NKG7 NRM PEX10 PEX19 PEX5 PNLIPRP1 PTPN9 RBFA SEC22A SEC61G SMCO4 SRGN STX8 THSD7B TMEM11 TMEM222 TREX1 TTPA
Entrez ID		389336	5193
HPRD ID		14491	03455
Ensembl ID		ENSG00000178776	ENSG00000108733
Uniprot IDs		Q6UWT4	O00623
PDB IDs
Enriched GO Terms of Interacting Partners?
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