ING1 and BRMS1

Data Source:
HPRD (in vivo)

		ING1	BRMS1
Description		inhibitor of growth family member 1	BRMS1 transcriptional repressor and anoikis regulator
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GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex
	Molecular Function	Protein Binding Methylated Histone Binding Metal Ion Binding	Protein Binding Histone Deacetylase Binding NF-kappaB Binding
	Biological Process	Cell Cycle Negative Regulation Of Cell Population Proliferation Regulation Of Cell Death Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis
Pathways			HDACs deacetylate histones Potential therapeutics for SARS
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Erosive tooth wear (severe vs non-severe) ( 29898447)	Bipolar disorder ( 21926972 31043756)
Interacting Genes		29 interacting genes: BRMS1 BRMS1L COPS2 CYTOR DMAP1 EP300 ESR1 EXOC4 H3C14 HDAC1 HDAC2 KAT2B MRGBP NQO1 PCNA RBBP4 RBBP7 RBP1 SAP30 SFN SIN3A TP53 UBC YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	49 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MCRS1 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1
Entrez ID		3621	25855
HPRD ID		03337	05879
Ensembl ID		ENSG00000153487	ENSG00000174744
Uniprot IDs		A0A0C4DFW2 Q9UK53	G5E9I4 Q9HCU9
PDB IDs		2QIC	2XUS 4AUV
Enriched GO Terms of Interacting Partners?
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