ING1 and EXOC4

Data Source:
BioGRID (two hybrid)

		ING1	EXOC4
Description		inhibitor of growth family member 1	exocyst complex component 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Exocyst Cytoplasm Cytosol Plasma Membrane Microvillus Membrane Growth Cone Membrane Myelin Sheath Abaxonal Region Synapse Flemming Body
	Molecular Function	Protein Binding Methylated Histone Binding Metal Ion Binding	Protein Binding PDZ Domain Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	Cell Cycle Negative Regulation Of Cell Population Proliferation Regulation Of Cell Death Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated	Protein Targeting To Membrane Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Chemical Synaptic Transmission Regulation Of Macroautophagy Paraxial Mesoderm Formation Vesicle Tethering Involved In Exocytosis
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Erosive tooth wear (severe vs non-severe) ( 29898447)	Alzheimer's disease (cognitive decline) ( 23535033) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Food allergy ( 29030101) Fruit consumption ( 32066663) General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Moderate to vigorous physical activity levels ( 29899525) Mood instability ( 31168069) Peanut allergy ( 29030101) Plasma anti-thyroid peroxidase levels ( 29678681) QT interval ( 29213071) Response to selective serotonin reuptake inhibitors in depression ( 30034349) Subcortical volume (MOSTest) ( 32665545) Tonometry ( 17903302) Vigorous physical activity ( 29899525)
Interacting Genes		29 interacting genes: BRMS1 BRMS1L COPS2 CYTOR DMAP1 EP300 ESR1 EXOC4 H3C14 HDAC1 HDAC2 KAT2B MRGBP NQO1 PCNA RBBP4 RBBP7 RBP1 SAP30 SFN SIN3A TP53 UBC YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	14 interacting genes: BIRC6 CCHCR1 CEP63 DISC1 DLG3 DLG4 DLGAP4 EXOC7 GOLGA1 GRIN2B ING1 MBD3 RALA SMARCE1
Entrez ID		3621	60412
HPRD ID		03337	12185
Ensembl ID		ENSG00000153487	ENSG00000131558
Uniprot IDs		A0A0C4DFW2 Q9UK53	Q6NX51 Q96A65
PDB IDs		2QIC
Enriched GO Terms of Interacting Partners?
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