IL13RA2 and RB1CC1

Data Source:
BioGRID (two hybrid)

		IL13RA2	RB1CC1
Description		interleukin 13 receptor subunit alpha 2	RB1 inducible coiled-coil 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space External Side Of Plasma Membrane Integral Component Of Membrane Receptor Complex	Phagophore Assembly Site Autophagosome Membrane Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	Cytokine Receptor Activity Protein Binding Cytokine Binding	Protein Binding Protein Kinase Binding Molecular Adaptor Activity
	Biological Process	Negative Regulation Of Immunoglobulin Production Immunoglobulin Mediated Immune Response Cytokine-mediated Signaling Pathway Negative Regulation Of Mast Cell Degranulation	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Interleukin-4 and Interleukin-13 signaling	Macroautophagy
Drugs		AER001
Diseases
GWAS			Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		17 interacting genes: AKT1 BAG4 BRMS1 CASP8 EGFR ERBB2 ESR2 IGF1R IL13 IL4 IL4R NOTCH2 PALB2 PAX2 PIK3CA PLPP6 RB1CC1	33 interacting genes: AZI2 BAP1 BLID COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TAX1BP1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1
Entrez ID		3598	9821
HPRD ID		02132	06019
Ensembl ID		ENSG00000123496	ENSG00000023287
Uniprot IDs		Q14627	Q8TDY2
PDB IDs		3LB6	6DCE 6GMA
Enriched GO Terms of Interacting Partners?
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