RPS6KA6 and ADIRF

Data Source:
BioGRID (two hybrid)

		RPS6KA6	ADIRF
Description		ribosomal protein S6 kinase A6	adipogenesis regulatory factor
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Cytoplasm Mitochondrion Cytosol	Nucleus Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Ribosomal Protein S6 Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Molecular_function Protein Binding
	Biological Process	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Signal Transduction Central Nervous System Development Peptidyl-serine Phosphorylation Negative Regulation Of Embryonic Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Mesoderm Development	Cell Differentiation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Radiation Cellular Response To Cisplatin Regulation Of Response To Drug
Pathways		Recycling pathway of L1 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling RSK activation RSK activation	Transcriptional regulation of white adipocyte differentiation
Drugs		Fostamatinib
Diseases
GWAS
Interacting Genes		28 interacting genes: ADIRF APP CEBPZ CENPB CLEC3B DHX34 DNAJC13 DNMT1 ERG28 FBN3 FZD5 LMO4 MASP1 MED24 MICAL1 MPP1 NR4A1 RBPJ RPLP1 RXRA SAP30BP SPRED2 SPTBN4 SYNE4 UBE2I UFM1 ZNF227 ZNF746	3 interacting genes: GSK3B IL18 RPS6KA6
Entrez ID		27330	10974
HPRD ID		02250	16575
Ensembl ID		ENSG00000072133	ENSG00000148671
Uniprot IDs		Q9UK32	Q15847 Q5TBU5
PDB IDs		6G76 6G77 6G78
Enriched GO Terms of Interacting Partners?
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