ADIRF and RPS6KA6

Data Source:
BioGRID (two hybrid)

		ADIRF	RPS6KA6
Description		adipogenesis regulatory factor	ribosomal protein S6 kinase A6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Extracellular Exosome	Fibrillar Center Nucleoplasm Nucleolus Cytoplasm Mitochondrion Cytosol
	Molecular Function	Molecular_function Protein Binding	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Ribosomal Protein S6 Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Cell Differentiation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Radiation Cellular Response To Cisplatin Regulation Of Response To Drug	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Signal Transduction Central Nervous System Development Peptidyl-serine Phosphorylation Negative Regulation Of Embryonic Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Mesoderm Development
Pathways		Transcriptional regulation of white adipocyte differentiation	Recycling pathway of L1 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling RSK activation RSK activation
Drugs			Fostamatinib
Diseases
GWAS
Interacting Genes		3 interacting genes: GSK3B IL18 RPS6KA6	28 interacting genes: ADIRF APP CEBPZ CENPB CLEC3B DHX34 DNAJC13 DNMT1 ERG28 FBN3 FZD5 LMO4 MASP1 MED24 MICAL1 MPP1 NR4A1 RBPJ RPLP1 RXRA SAP30BP SPRED2 SPTBN4 SYNE4 UBE2I UFM1 ZNF227 ZNF746
Entrez ID		10974	27330
HPRD ID		16575	02250
Ensembl ID		ENSG00000148671	ENSG00000072133
Uniprot IDs		Q15847 Q5TBU5	Q9UK32
PDB IDs			6G76 6G77 6G78
Enriched GO Terms of Interacting Partners?
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