ZBED1 and NIP7

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZBED1	NIP7
Description		zinc finger BED-type containing 1	nucleolar pre-rRNA processing protein NIP7
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Centrosome PML Body Nuclear Membrane	Nucleoplasm Nucleolus Cytosol Preribosome, Large Subunit Precursor
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding SUMO Transferase Activity Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Protein Dimerization Activity SUMO Ligase Activity Sequence-specific Double-stranded DNA Binding	RNA Binding Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Viral Process Negative Regulation By Host Of Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Protein Autosumoylation	Ribosome Assembly Ribosomal Large Subunit Biogenesis
Pathways		SUMOylation of chromatin organization proteins	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs			Radezolid
Diseases
GWAS			Body mass index ( 26426971) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		55 interacting genes: AMOTL2 ATRX C1orf109 CCDC13 CDC37 CTNNAL1 DGCR6 EFHC1 FABP4 FAM124B FANCG FNDC11 GGACT GORASP2 GPN1 GPSM1 KDM1A KIFC3 KLHL40 LCN2 LNX1 LRRC20 MAD2L2 MAGEB2 MKKS MLH1 MPST MYO15B NCDN NIF3L1 NIP7 NTAQ1 NUDT18 PAX6 PIAS2 PICK1 POLE2 POLR1C PRKAA1 PRKAR1A PSAP RENBP RIN1 SORBS3 SPEF1 SSX2 SUMO2 TRAPPC2 TRAPPC2B TRIML2 TTC23 TTR UBE2I UCHL5 USP2	5 interacting genes: CRX LZTS2 NECAB2 NOL8 ZBED1
Entrez ID		9189	51388
HPRD ID		02170	16709
Ensembl ID		ENSG00000214717	ENSG00000132603
Uniprot IDs		A0A024RBU4 O96006	Q9Y221
PDB IDs		2CT5	1SQW 1T5Y
Enriched GO Terms of Interacting Partners?
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