ZBED1 and SPEF1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZBED1	SPEF1
Description		zinc finger BED-type containing 1	sperm flagellar 1
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Centrosome PML Body Nuclear Membrane	Cytoplasm Microtubule Microvillus Axoneme Basolateral Plasma Membrane Apical Plasma Membrane Lamellipodium Filopodium Ciliary Tip 9+2 Motile Cilium Axonemal Central Apparatus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding SUMO Transferase Activity Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Protein Dimerization Activity SUMO Ligase Activity Sequence-specific Double-stranded DNA Binding	Molecular_function Actin Binding Protein Binding Microtubule Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Viral Process Negative Regulation By Host Of Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Protein Autosumoylation	Microtubule Bundle Formation Cilium Movement Negative Regulation Of Microtubule Depolymerization Cell Migration Lamellipodium Assembly Filopodium Assembly Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axonemal Central Apparatus Assembly Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways		SUMOylation of chromatin organization proteins
Drugs
Diseases
GWAS			Cognitive decline rate in late mild cognitive impairment ( 26252872) Hippocampal volume ( 29860282) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		55 interacting genes: AMOTL2 ATRX C1orf109 CCDC13 CDC37 CTNNAL1 DGCR6 EFHC1 FABP4 FAM124B FANCG FNDC11 GGACT GORASP2 GPN1 GPSM1 KDM1A KIFC3 KLHL40 LCN2 LNX1 LRRC20 MAD2L2 MAGEB2 MKKS MLH1 MPST MYO15B NCDN NIF3L1 NIP7 NTAQ1 NUDT18 PAX6 PIAS2 PICK1 POLE2 POLR1C PRKAA1 PRKAR1A PSAP RENBP RIN1 SORBS3 SPEF1 SSX2 SUMO2 TRAPPC2 TRAPPC2B TRIML2 TTC23 TTR UBE2I UCHL5 USP2	5 interacting genes: CYSRT1 KRT40 KRTAP13-2 PLEKHF2 ZBED1
Entrez ID		9189	25876
HPRD ID		02170	09839
Ensembl ID		ENSG00000214717	ENSG00000101222
Uniprot IDs		A0A024RBU4 O96006	Q9Y4P9
PDB IDs		2CT5	2EE7
Enriched GO Terms of Interacting Partners?
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