FAM83A and PPP1R16B

Data Source:
BioGRID (two hybrid)

		FAM83A	PPP1R16B
Description		family with sequence similarity 83 member A	protein phosphatase 1 regulatory subunit 16B
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Plasma Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein Kinase Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding Identical Protein Binding	Protein Binding Protein Phosphatase 1 Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity
	Biological Process	Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Cell Population Proliferation	Positive Regulation Of Endothelial Cell Proliferation Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Protein Dephosphorylation Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Filopodium Assembly Establishment Of Endothelial Barrier Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis
Pathways
Drugs
Diseases
GWAS		Urinary uromodulin levels ( 24578125)	Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diverticular disease ( 30177863) Huntington's disease progression ( 28642124) Mean corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes		23 interacting genes: BHLHE40 CYSRT1 DAZAP2 FOXH1 FOXI1 GCC1 GPSM1 KRT34 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 MGAT5B NCK2 PLAGL2 PPP1R16B PRDM14 PSMA3 QARS1 SMYD1 TRIM23 TRIM27 UBASH3A	37 interacting genes: ATPAF2 CDCA7L CEP55 CEP70 CRX DVL2 DVL3 FAM83A FARS2 FLYWCH1 GATA1 GFAP GOLGA2 HAPLN2 IKZF3 KCTD9 MAGOH MISP NEFL PATZ1 PHC2 PLEKHN1 PPP1CA PPP1CB RBPMS RFC5 SCNM1 SF3B4 SHC3 TACO1 TADA2A TASOR2 TFIP11 TLE5 TXN2 ZNF410 ZNF564
Entrez ID		84985	26051
HPRD ID		17489	15168
Ensembl ID		ENSG00000147689	ENSG00000101445
Uniprot IDs		Q86UY5	Q96T49
PDB IDs		4URJ
Enriched GO Terms of Interacting Partners?
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