RBP1 and UBE2J2

Data Source:
BioGRID (two hybrid)

		RBP1	UBE2J2
Description		retinol binding protein 1	ubiquitin conjugating enzyme E2 J2
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GO Annotations	Cellular Component	Nucleoplasm Lipid Droplet Cytosol	Ubiquitin Ligase Complex Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Retinoid Binding Protein Binding Retinal Binding All-trans-retinol Binding	Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Retinoid Metabolic Process Retinoic Acid Biosynthetic Process Vitamin A Metabolic Process Lipid Homeostasis	Protein Polyubiquitination Response To Unfolded Protein Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Positive Regulation Of Protein Targeting To Mitochondrion
Pathways		Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) Retinoid metabolism and transport	E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Acitretin
Diseases
GWAS			Inflammatory bowel disease ( 28067908) Systemic lupus erythematosus ( 28714469) Ulcerative colitis ( 28067908)
Interacting Genes		18 interacting genes: BRMS1 BRMS1L CYTOR DHPS HDAC1 HDAC2 IKBKG ING1 LRAT LRP2 MED26 RBBP4 RBBP7 SAP30 SIN3A TNFRSF10D TTC19 UBE2J2	21 interacting genes: AQP6 ATP13A2 ELOVL7 FBXO7 HECW1 HERC4 ITCH MDM2 MGRN1 NEDD4L PRKN RBP1 RNF10 TMEM14B TRIM25 TRIM59 UBA1 UBC UBE2G2 WWP2 XIAP
Entrez ID		5947	118424
HPRD ID		07036	15600
Ensembl ID		ENSG00000114115	ENSG00000160087
Uniprot IDs		A0A0A0MQT0 P09455	A0A024R075 A6NGS0 Q8N2K1
PDB IDs		5H8T 5H9A 5HA1 5HBS 5LJB 5LJC 5LJD 5LJE 5LJG 5LJH 5LJK 6E5L 6E5T 6E6M	2F4W
Enriched GO Terms of Interacting Partners?
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