RBP1 and RBBP7

Data Source:
HPRD (in vivo)

		RBP1	RBBP7
Description		retinol binding protein 1	RB binding protein 7, chromatin remodeling factor
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GO Annotations	Cellular Component	Nucleoplasm Lipid Droplet Cytosol	Nucleus Nucleoplasm Cytosol NuRD Complex ESC/E(Z) Complex
	Molecular Function	Retinoid Binding Protein Binding Retinal Binding All-trans-retinol Binding	RNA Binding Protein Binding
	Biological Process	Retinoid Metabolic Process Retinoic Acid Biosynthetic Process Vitamin A Metabolic Process Lipid Homeostasis	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Negative Regulation Of Cell Growth CENP-A Containing Nucleosome Assembly Post-translational Protein Modification Negative Regulation Of Gene Expression, Epigenetic Response To Steroid Hormone Negative Regulation Of G0 To G1 Transition Cellular Heat Acclimation Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) Retinoid metabolism and transport	PRC2 methylates histones and DNA Oxidative Stress Induced Senescence HDACs deacetylate histones PKMTs methylate histone lysines HATs acetylate histones RMTs methylate histone arginines ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Activation of anterior HOX genes in hindbrain development during early embryogenesis Deposition of new CENPA-containing nucleosomes at the centromere Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Neddylation Transcriptional Regulation by E2F6 HCMV Early Events Potential therapeutics for SARS
Drugs		Acitretin
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		18 interacting genes: BRMS1 BRMS1L CYTOR DHPS HDAC1 HDAC2 IKBKG ING1 LRAT LRP2 MED26 RBBP4 RBBP7 SAP30 SIN3A TNFRSF10D TTC19 UBE2J2	34 interacting genes: APPL1 APPL2 BCL11A BCL11B BRCA1 BRMS1 BRMS1L BUB3 CREBBP CYTOR DHX30 ERCC6 ESR1 FOXK2 H3-4 H3C1 HDAC1 HDAC2 HUWE1 ING1 MBD3 MBD3L2 MTA2 NR2E3 PRKAA2 RB1 RBBP4 RBP1 SALL2 SAP30 SIN3A SUMO2 SUV39H1 TWIST1
Entrez ID		5947	5931
HPRD ID		07036	04231
Ensembl ID		ENSG00000114115	ENSG00000102054
Uniprot IDs		A0A0A0MQT0 P09455	Q16576 Q6FHQ0
PDB IDs		5H8T 5H9A 5HA1 5HBS 5LJB 5LJC 5LJD 5LJE 5LJG 5LJH 5LJK 6E5L 6E5T 6E6M	3CFS 3CFV
Enriched GO Terms of Interacting Partners?
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