EVPL and SPRR3

Data Source:
HPRD (in vivo)

		EVPL	SPRR3
Description		envoplakin	small proline rich protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Cytosol Intermediate Filament Membrane Desmosome Intermediate Filament Cytoskeleton Extracellular Exosome	Cornified Envelope Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Structural Molecule Activity Intermediate Filament Binding Cadherin Binding	Structural Molecule Activity Protein Binding
	Biological Process	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Wound Healing Intermediate Filament Cytoskeleton Organization Cornification	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Wound Healing Cornification
Pathways		Formation of the cornified envelope	Formation of the cornified envelope
Drugs
Diseases
GWAS		Deep white matter hyperintensities ( 32517579) Depressive symptom improvement ( 30468137) L-selectin levels ( 25576479) Metabolite levels ( 23823483) Periventricular white matter hyperintensities ( 32517579)	Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Inflammatory skin disease ( 25574825)
Interacting Genes		14 interacting genes: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LORICRIN PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3	3 interacting genes: EVPL IVL LORICRIN
Entrez ID		2125	6707
HPRD ID		03352	01652
Ensembl ID		ENSG00000167880	ENSG00000163209
Uniprot IDs		B7ZLH8 K7EKI0 Q92817	Q9UBC9
PDB IDs		4QMD
Enriched GO Terms of Interacting Partners?
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