EVPL and LORICRIN

Data Source:
HPRD (in vivo)

		EVPL	LORICRIN
Description		envoplakin	loricrin cornified envelope precursor protein
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Cytosol Intermediate Filament Membrane Desmosome Intermediate Filament Cytoskeleton Extracellular Exosome	Cornified Envelope Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Structural Molecule Activity Intermediate Filament Binding Cadherin Binding	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Wound Healing Intermediate Filament Cytoskeleton Organization Cornification	Cytoskeleton Organization Peptide Cross-linking Keratinocyte Differentiation Cornification
Pathways		Formation of the cornified envelope	Formation of the cornified envelope
Drugs
Diseases			Vohwinkel syndrome, including: Vohwinkel syndrome (VS); Vohwinkel syndrome with ichthyosis
GWAS		Deep white matter hyperintensities ( 32517579) Depressive symptom improvement ( 30468137) L-selectin levels ( 25576479) Metabolite levels ( 23823483) Periventricular white matter hyperintensities ( 32517579)
Interacting Genes		14 interacting genes: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LORICRIN PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3	7 interacting genes: CSTA EVPL IVL KRT1 PI3 SPRR3 VIM
Entrez ID		2125	4014
HPRD ID		03352	01070
Ensembl ID		ENSG00000167880	ENSG00000203782
Uniprot IDs		B7ZLH8 K7EKI0 Q92817	P23490
PDB IDs		4QMD
Enriched GO Terms of Interacting Partners?
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