EVPL and SPRR2A

Data Source:
HPRD (in vivo)

		EVPL	SPRR2A
Description		envoplakin	small proline rich protein 2A
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Cytosol Intermediate Filament Membrane Desmosome Intermediate Filament Cytoskeleton Extracellular Exosome	Cornified Envelope Cytoplasm Cytosol
	Molecular Function	Structural Molecule Activity Intermediate Filament Binding Cadherin Binding	Protein Binding
	Biological Process	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Wound Healing Intermediate Filament Cytoskeleton Organization Cornification	Epidermis Development Keratinocyte Differentiation Cornification
Pathways		Formation of the cornified envelope	Formation of the cornified envelope
Drugs
Diseases
GWAS		Deep white matter hyperintensities ( 32517579) Depressive symptom improvement ( 30468137) L-selectin levels ( 25576479) Metabolite levels ( 23823483) Periventricular white matter hyperintensities ( 32517579)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		14 interacting genes: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LORICRIN PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3	10 interacting genes: ABL1 AKT2 CRK CTTN DLG4 EVPL HCK ITK PEX13 YES1
Entrez ID		2125	6700
HPRD ID		03352	01649
Ensembl ID		ENSG00000167880	ENSG00000241794
Uniprot IDs		B7ZLH8 K7EKI0 Q92817	P35326
PDB IDs		4QMD
Enriched GO Terms of Interacting Partners?
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