EVPL and PSORS1C2

Data Source:
HPRD (in vivo)

		EVPL	PSORS1C2
Description		envoplakin	psoriasis susceptibility 1 candidate 2
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Cytosol Intermediate Filament Membrane Desmosome Intermediate Filament Cytoskeleton Extracellular Exosome	Cellular_component Extracellular Region
	Molecular Function	Structural Molecule Activity Intermediate Filament Binding Cadherin Binding	Molecular_function Protein Binding
	Biological Process	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Wound Healing Intermediate Filament Cytoskeleton Organization Cornification	Biological_process
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Deep white matter hyperintensities ( 32517579) Depressive symptom improvement ( 30468137) L-selectin levels ( 25576479) Metabolite levels ( 23823483) Periventricular white matter hyperintensities ( 32517579)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Broad depression or schizophrenia ( 30626913) Height ( 28552196 25282103) Hematology traits ( 23263863) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Metabolite levels ( 23823483) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Night sleep phenotypes ( 27126917) Serum uric acid levels ( 30993211) Ulcerative colitis ( 28067908) White blood cell count ( 21738480)
Interacting Genes		14 interacting genes: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LORICRIN PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3	27 interacting genes: AGR2 AP1B1 AP2B1 BANP CEP70 ERICH2 EVPL GUCA1C HMG20A HOMER3 LHX3 MED20 MEIS3 MYL2 MYL7 NCKIPSD PAX6 PEX19 REL RTRAF SERTAD1 SGTA SGTB TTC23 UBQLN1 UBQLN2 VASP
Entrez ID		2125	170680
HPRD ID		03352	17921
Ensembl ID		ENSG00000167880	ENSG00000204538
Uniprot IDs		B7ZLH8 K7EKI0 Q92817	A0A1U9X9A6 Q9UIG4
PDB IDs		4QMD
Enriched GO Terms of Interacting Partners?
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