SPRY1 and ADAM12

  • Data Source:
  • BioGRID (two hybrid)

SPRY1

ADAM12

Description sprouty RTK signaling antagonist 1 ADAM metallopeptidase domain 12
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein B levels ( 32203549)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Irritable bowel syndrome ( 24797007)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Metabolite levels ( 23823483)
  • Pelvic organ prolapse ( 26545240)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858)
  • Triglyceride levels ( 32203549)
  • Blood protein levels ( 30072576)
  • Endometrial cancer ( 24096698)
  • Extremely high intelligence ( 29731509)
  • Heel bone mineral density ( 30598549)
  • Intraocular pressure ( 30054594)
  • Itch intensity from mosquito bite ( 28199695)
  • Loneliness ( 27629369)
  • Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
  • Mild influenza (H1N1) infection ( 26379185)
  • Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070 27021288)
  • Placental abruption ( 29884306)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Visceral fat ( 22589738)
Interacting Genes 83 interacting genes: ADAM12 ADAMTSL4 ANKRD11 ATXN7 CACNA1A CCDC57 CDR2L CHRD CREB5 CYSRT1 FARS2 FBLN1 FHL5 GEMIN4 GNE GRB2 GUCD1 HEXIM2 HOXA1 HRG HSF2BP INCA1 KPNA2 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2A LCE2C LCE2D LCE3A LCE3C LCE3D LCE4A LCE5A MB21D2 MDFI MEOX2 NBPF19 NOTCH2NLA NTM OTX1 PCSK5 POLR1C PRKAA2 PRKAB2 R3HDM2 REL SMCP SOCS4 SPRY2 STAT3 TFAP2D TGM7 UBASH3A VWC2 YY1 ZNF23 ZNF330 ZNF417 ZNF441 ZNF837 40 interacting genes: ACTN2 ADAMTSL4 CYSRT1 EGF ESM1 FHL5 FSTL3 GRB2 GUCD1 HOXA1 IGFBP3 IGFBP5 KRT83 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP12-2 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP5-6 KRTAP5-9 KRTAP6-2 KRTAP9-2 KRTAP9-8 LCE5A MAPKBP1 NBPF19 NOTCH2NLA OTX1 PACSIN3 PIK3R1 RECK SH3D19 SLC15A2 SPRY1 SPRY4 SRC TFAP2D YES1
Entrez ID 10252 8038
HPRD ID 06782 04092
Ensembl ID ENSG00000164056 ENSG00000148848
Uniprot IDs O43609 A8K6G4 O43184 U5NE98
PDB IDs
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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