SPRY1 and CREB5

  • Data Source:
  • BioGRID (two hybrid, two hybrid)

SPRY1

CREB5

Description sprouty RTK signaling antagonist 1 cAMP responsive element binding protein 5
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein B levels ( 32203549)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Irritable bowel syndrome ( 24797007)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Metabolite levels ( 23823483)
  • Pelvic organ prolapse ( 26545240)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858)
  • Triglyceride levels ( 32203549)
  • Adolescent idiopathic scoliosis ( 31417091)
  • Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325)
  • Age-related cognitive decline (memory) (slope of z-scores) ( 30954325)
  • Airflow obstruction ( 22837378)
  • Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals ( 22959728)
  • Anxiety in major depressive disorder ( 24047446)
  • Asthma ( 31959851)
  • Asthma (childhood onset) ( 31036433)
  • Atrial fibrillation ( 30061737 29892015)
  • Attention deficit hyperactivity disorder ( 18839057)
  • Basophil count ( 32888494)
  • Basophil percentage of white cells ( 32888494)
  • Blond vs. brown/black hair color ( 30531825)
  • Breast cancer ( 29059683)
  • Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) ( 31372216)
  • Crohn's disease ( 23128233)
  • Diabetic retinopathy ( 21441570)
  • Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Granulocyte count ( 27863252)
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • Hand grip strength ( 29691431)
  • Heel bone mineral density ( 30598549 28869591)
  • Height ( 28552196)
  • Lymphocyte percentage of white cells ( 32888494 27863252)
  • Monocyte percentage of white cells ( 32888494 27863252)
  • Myeloid white cell count ( 27863252)
  • Neutrophil count ( 29403010 32888494 27863252)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Neutrophil percentage of white cells ( 32888494 27863252)
  • Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Pulse pressure ( 27841878 30578418)
  • Serum thyroid-stimulating hormone levels ( 25436638)
  • Smoking behaviour (cigarettes smoked per day) ( 31217584)
  • Sum basophil neutrophil counts ( 27863252)
  • Sum neutrophil eosinophil counts ( 27863252)
  • TPE interval (resting) ( 32386560)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • White blood cell count ( 29403010 32888494 27863252)
  • White blood cell count (basophil) ( 27863252)
Interacting Genes 83 interacting genes: ADAM12 ADAMTSL4 ANKRD11 ATXN7 CACNA1A CCDC57 CDR2L CHRD CREB5 CYSRT1 FARS2 FBLN1 FHL5 GEMIN4 GNE GRB2 GUCD1 HEXIM2 HOXA1 HRG HSF2BP INCA1 KPNA2 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2A LCE2C LCE2D LCE3A LCE3C LCE3D LCE4A LCE5A MB21D2 MDFI MEOX2 NBPF19 NOTCH2NLA NTM OTX1 PCSK5 POLR1C PRKAA2 PRKAB2 R3HDM2 REL SMCP SOCS4 SPRY2 STAT3 TFAP2D TGM7 UBASH3A VWC2 YY1 ZNF23 ZNF330 ZNF417 ZNF441 ZNF837 132 interacting genes: ADAMTSL4 AJUBA AKAP8L ALPP ANAPC11 ATF2 BATF3 CDPF1 CERCAM CIB4 CNFN COL8A1 CYP21A2 CYSRT1 EFEMP2 FBLN1 FHL3 FOS FOSB FOSL1 FOSL2 FRS3 FST HOXA1 HSD3B7 ID3 IGFBP6 INTS11 JDP2 JUN KIFC3 KPRP KRT15 KRT31 KRT40 KRT83 KRT85 KRT86 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP19-2 KRTAP19-3 KRTAP19-5 KRTAP19-6 KRTAP2-3 KRTAP2-4 KRTAP22-1 KRTAP3-1 KRTAP3-2 KRTAP4-1 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1C LCE2A LCE2C LCE4A LCE5A LGALS13 LITAF LMX1B MDFI MGAT5B MLLT6 MMADHC MTUS2 NADSYN1 NBPF19 NOTCH2NLA PCSK5 PLA2G10 PRDM14 PRR22 RBCK1 RBP3 RBPMS RCHY1 RGS17 RGS20 RIMBP3 RNF144B RNF208 SIVA1 SNAPC5 SPATA12 SPOP SPOPL SPRED1 SPRY1 SPRY2 SPRY3 SPRY4 SSC4D TP53BP1 TRAF2 TRIM23 TRIM27 TRIM42 TRIP6 TSGA10 TSPAN4 TSR2 UFSP1 UNKL WWOX ZMAT5 ZNF330
Entrez ID 10252 9586
HPRD ID 06782 09896
Ensembl ID ENSG00000164056 ENSG00000146592
Uniprot IDs O43609 Q02930
PDB IDs
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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