CHAF1A and MEI4

Data Source:
BioGRID (two hybrid)

		CHAF1A	MEI4
Description		chromatin assembly factor 1 subunit A	meiotic double-stranded break formation protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Protein-containing Complex CAF-1 Complex	Lateral Element
	Molecular Function	Chromatin Binding Protein Binding Identical Protein Binding Unfolded Protein Binding Chromo Shadow Domain Binding	Protein Binding
	Biological Process	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis
Pathways
Drugs
Diseases
GWAS		Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)	Brain volume in infants (white matter) ( 28763065) Cadmium levels ( 26025379) Macular thickness ( 30535121)
Interacting Genes		47 interacting genes: ANP32A ANP32B ASF1A ASF1B BLM CBX1 CBX5 CDC7 CDK2 CHAF1B CREBBP DBF4 DDX41 H3-4 H3C6 HMGB2 LZTR1 MBD1 MEI4 MSH6 NOTO PABPC1 PAX6 PCBD2 PCNA POU6F2 RBFOX2 REL SERTAD1 SET SPOP STAT5B SUMO1 SUMO2 SUMO3 TCERG1 TCF4 TRIB3 TRIM28 XRCC5 XRCC6 YWHAB YWHAE YWHAG YWHAQ ZNF408 ZNF620	36 interacting genes: AFMID BAG4 C19orf25 C1orf109 CABP5 CDKN2D CHAF1A CPNE2 CST9L CTTNBP2 DNTT EIF5A FKBP6 GRB2 HSD3B7 IQGAP1 LGALS14 MACO1 METTL21A MLX MTMR9 MYO5B NGB NME7 OSGIN1 PAFAH1B3 PHYHIPL PLEKHA4 POLR1C R3HDM2 TRAPPC2L TRIM59 TSEN15 TSSK3 USHBP1 VPS26C
Entrez ID		10036	101928601
HPRD ID		03148
Ensembl ID		ENSG00000167670	ENSG00000269964
Uniprot IDs		Q13111	A8MW99
PDB IDs
Enriched GO Terms of Interacting Partners?
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