SH3GLB2 and GIT2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SH3GLB2	GIT2
Description		SH3 domain containing GRB2 like, endophilin B2	GIT ArfGAP 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Nucleoplasm Focal Adhesion
	Molecular Function	Protein Binding Identical Protein Binding Cadherin Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process		Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Catalytic Activity
Pathways			CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Serum metabolite concentrations in chronic kidney disease ( 33838163)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)
Interacting Genes		38 interacting genes: CCDC158 CCND3 CDKN2D CNOT7 EFHC1 EXOSC1 EXOSC5 FHL3 FXR1 GAA GADD45G GIT2 GOLGA2 KDM1A KRTAP10-1 KRTAP10-8 KRTAP4-5 KRTAP5-11 KRTAP9-3 LGALS14 LNX2 LSM3 MAGEA1 MORF4L1 NMI NTAQ1 NXF1 OGT PICK1 SH3GLB1 SH3KBP1 SREK1 STX4 TBC1D7 TEX11 TRAF1 TSG101 YES1	48 interacting genes: ACTG1 ACTN1 ARHGEF6 ARHGEF7 ATF5 C4BPA CALCOCO2 CDC42 CORO1A E2F2 EDC4 GCH1 GET4 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LAMTOR5 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG
Entrez ID		56904	9815
HPRD ID		15334	09779
Ensembl ID		ENSG00000148341	ENSG00000139436
Uniprot IDs		A0A024R896 B7ZC38 Q9NR46	F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58
PDB IDs
Enriched GO Terms of Interacting Partners?
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