GIT2 and QPRT

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GIT2	QPRT
Description		GIT ArfGAP 2	quinolinate phosphoribosyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Focal Adhesion	Cytoplasm Cytosol Extracellular Exosome Catalytic Complex
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Nicotinate-nucleotide Diphosphorylase (carboxylating) Activity Protein Binding Identical Protein Binding
	Biological Process	Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Catalytic Activity	NAD Biosynthetic Process NAD Metabolic Process Quinolinate Catabolic Process
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle	Nicotinate metabolism
Drugs			Niacin
Diseases
GWAS		Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)
Interacting Genes		48 interacting genes: ACTG1 ACTN1 ARHGEF6 ARHGEF7 ATF5 C4BPA CALCOCO2 CDC42 CORO1A E2F2 EDC4 GCH1 GET4 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LAMTOR5 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG	11 interacting genes: ADAMTSL4 BCKDK ETS1 GIT2 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-8 KRTAP4-12 NOTCH2NLA SUFU
Entrez ID		9815	23475
HPRD ID		09779	06950
Ensembl ID		ENSG00000139436	ENSG00000103485
Uniprot IDs		F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58	B4DDH4 Q15274 V9HWJ5
PDB IDs			2JBM 4KWV 4KWW 5AYX 5AYY 5AYZ
Enriched GO Terms of Interacting Partners?
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