SH3GLB2 and CNOT7

Number of citations of the paper that reports this interaction (PubMedID 30217970)
5

Data Source:
BioGRID (two hybrid)

		SH3GLB2	CNOT7
Description		SH3 domain containing GRB2 like, endophilin B2	CCR4-NOT transcription complex subunit 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	P-body Nucleus Cytoplasm Cytosol Membrane Nuclear Body Nuclear Speck CCR4-NOT Complex CCR4-NOT Core Complex
	Molecular Function	Protein Binding Identical Protein Binding Cadherin Binding	3'-5'-exoribonuclease Activity Transcription Corepressor Activity RNA Binding Exoribonuclease Activity Poly(A)-specific Ribonuclease Activity Protein Binding Metal Ion Binding DNA-binding Transcription Factor Binding
	Biological Process		Nuclear-transcribed MRNA Poly(A) Tail Shortening Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Gene Silencing By RNA P-body Assembly Gene Silencing By MiRNA Regulation Of Tyrosine Phosphorylation Of STAT Protein Exonucleolytic Catabolism Of Deadenylated MRNA Positive Regulation Of Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Pathways			Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Serum metabolite concentrations in chronic kidney disease ( 33838163)
Interacting Genes		38 interacting genes: CCDC158 CCND3 CDKN2D CNOT7 EFHC1 EXOSC1 EXOSC5 FHL3 FXR1 GAA GADD45G GIT2 GOLGA2 KDM1A KRTAP10-1 KRTAP10-8 KRTAP4-5 KRTAP5-11 KRTAP9-3 LGALS14 LNX2 LSM3 MAGEA1 MORF4L1 NMI NTAQ1 NXF1 OGT PICK1 SH3GLB1 SH3KBP1 SREK1 STX4 TBC1D7 TEX11 TRAF1 TSG101 YES1	29 interacting genes: ALMS1 APP BTG1 BTG2 BTG3 CDK1 CDK2 CDK4 CDK6 CNOT6 FBXO7 FHL3 FOXC2 HOXD4 IKBKG LSM3 MRFAP1L1 NMI PABPC1 PIAS1 PSMC1 PSMC2 SCARA3 SH3GLB2 TCP11L1 TEX11 TOB1 TOB2 TSG101
Entrez ID		56904	29883
HPRD ID		15334	05370
Ensembl ID		ENSG00000148341	ENSG00000198791
Uniprot IDs		A0A024R896 B7ZC38 Q9NR46	Q96IQ6 Q9UIV1
PDB IDs			2D5R 4GMJ
Enriched GO Terms of Interacting Partners?
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