TRIM14 and ALG13

Number of citations of the paper that reports this interaction (PubMedID 29053956)
17

Data Source:
BioGRID (two hybrid)

		TRIM14	ALG13
Description		tripartite motif containing 14	ALG13 UDP-N-acetylglucosaminyltransferase subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane	Endoplasmic Reticulum Membrane
	Molecular Function	Molecular_function Zinc Ion Binding	RNA Binding N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Activity Thiol-dependent Ubiquitinyl Hydrolase Activity
	Biological Process	Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity	Dolichol-linked Oligosaccharide Biosynthetic Process Proteolysis
Pathways		Interferon gamma signaling	Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)	Rosacea symptom severity ( 29771307)
Interacting Genes		52 interacting genes: ABCF3 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H CENPC CSPP1 EIF3G ETFBKMT FAT1 HERC3 ITM2A IVNS1ABP KAT2B KIF3A LAMTOR1 MITD1 MNAT1 MRPL24 NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR2G PPP2R3C RAB5A RAB9A RBM33 RLF RNF125 RNF20 SMARCB1 SMIM3 STK38 TAX1BP1 TMEM167A UBE2B UBE2N UNK WDR35 WRNIP1 ZC4H2 ZFP36L2 ZNF652	9 interacting genes: ATN1 ATXN1L HOXA1 MAPKBP1 PITX1 RBFOX1 RERE RHOU TRIM14
Entrez ID		9830	79868
HPRD ID		05948	06542
Ensembl ID		ENSG00000106785	ENSG00000101901
Uniprot IDs		A0A024R165 Q14142	A0A087WT15 A0A087WX43 Q9NP73
PDB IDs
Enriched GO Terms of Interacting Partners?
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