TRIM14 and LAMTOR1

Number of citations of the paper that reports this interaction (PubMedID 29053956)
17

Data Source:
BioGRID (two hybrid)

		TRIM14	LAMTOR1
Description		tripartite motif containing 14	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane	Lysosome Lysosomal Membrane Plasma Membrane Late Endosome Membrane Azurophil Granule Membrane Specific Granule Membrane Membrane Raft Extracellular Exosome Ragulator Complex Ficolin-1-rich Granule Membrane
	Molecular Function	Molecular_function Zinc Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding GTPase Binding Molecular Adaptor Activity
	Biological Process	Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity	Regulation Of Cell Growth Regulation Of Receptor Recycling Endosome Organization Lysosome Organization Cell Cycle Arrest Regulation Of Cholesterol Esterification Regulation Of Cholesterol Efflux Endosomal Transport Regulation Of Macroautophagy Positive Regulation Of TOR Signaling Lysosome Localization Cellular Protein Localization Cholesterol Homeostasis Neutrophil Degranulation Positive Regulation Of MAPK Cascade Regulation Of Cholesterol Import Cellular Response To Amino Acid Stimulus
Pathways		Interferon gamma signaling	Macroautophagy mTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Neutrophil degranulation Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)
Interacting Genes		52 interacting genes: ABCF3 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H CENPC CSPP1 EIF3G ETFBKMT FAT1 HERC3 ITM2A IVNS1ABP KAT2B KIF3A LAMTOR1 MITD1 MNAT1 MRPL24 NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR2G PPP2R3C RAB5A RAB9A RBM33 RLF RNF125 RNF20 SMARCB1 SMIM3 STK38 TAX1BP1 TMEM167A UBE2B UBE2N UNK WDR35 WRNIP1 ZC4H2 ZFP36L2 ZNF652	5 interacting genes: ABCF3 CAPN1 CCDC90B EEF1A1 TRIM14
Entrez ID		9830	55004
HPRD ID		05948	07933
Ensembl ID		ENSG00000106785	ENSG00000149357
Uniprot IDs		A0A024R165 Q14142	Q6IAA8
PDB IDs			5X6U 5X6V 5Y39 5Y3A 6B9X 6EHP 6EHR 6NZD 6U62 6ULG
Enriched GO Terms of Interacting Partners?
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