TRIM14 and CENPC

Number of citations of the paper that reports this interaction (PubMedID 29053956)
17

Data Source:
BioGRID (two hybrid)

		TRIM14	CENPC
Description		tripartite motif containing 14	centromere protein C
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane	Kinetochore Condensed Nuclear Chromosome Kinetochore Condensed Nuclear Chromosome, Centromeric Region Cell Nucleoplasm Pericentric Heterochromatin Cytosol Nuclear Body Midbody Nuclear Pericentric Heterochromatin
	Molecular Function	Molecular_function Zinc Ion Binding	DNA Binding Protein Binding Centromeric DNA Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity	Mitotic Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Cell Division Attachment Of Mitotic Spindle Microtubules To Kinetochore Kinetochore Assembly Attachment Of Spindle Microtubules To Kinetochore Involved In Homologous Chromosome Segregation
Pathways		Interferon gamma signaling	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)	Adverse response to drug ( 30420678) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)
Interacting Genes		52 interacting genes: ABCF3 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H CENPC CSPP1 EIF3G ETFBKMT FAT1 HERC3 ITM2A IVNS1ABP KAT2B KIF3A LAMTOR1 MITD1 MNAT1 MRPL24 NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR2G PPP2R3C RAB5A RAB9A RBM33 RLF RNF125 RNF20 SMARCB1 SMIM3 STK38 TAX1BP1 TMEM167A UBE2B UBE2N UNK WDR35 WRNIP1 ZC4H2 ZFP36L2 ZNF652	7 interacting genes: DAXX ELOC MAPK14 MDC1 SUMO2 TRIM14 UBTF
Entrez ID		9830	1060
HPRD ID		05948	00315
Ensembl ID		ENSG00000106785	ENSG00000145241
Uniprot IDs		A0A024R165 Q14142	Q03188
PDB IDs			5LSJ 5LSK 6MUO 6MUP 6SE6 6SEE 6SEF
Enriched GO Terms of Interacting Partners?
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