ALG13 and TRIM14

Number of citations of the paper that reports this interaction (PubMedID 29053956)
17

Data Source:
BioGRID (two hybrid)

		ALG13	TRIM14
Description		ALG13 UDP-N-acetylglucosaminyltransferase subunit	tripartite motif containing 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane	Mitochondrial Outer Membrane
	Molecular Function	RNA Binding N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Activity Thiol-dependent Ubiquitinyl Hydrolase Activity	Molecular_function Zinc Ion Binding
	Biological Process	Dolichol-linked Oligosaccharide Biosynthetic Process Proteolysis	Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)	Interferon gamma signaling
Drugs
Diseases
GWAS		Rosacea symptom severity ( 29771307)	Multiple sclerosis ( 31604244)
Interacting Genes		9 interacting genes: ATN1 ATXN1L HOXA1 MAPKBP1 PITX1 RBFOX1 RERE RHOU TRIM14	52 interacting genes: ABCF3 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H CENPC CSPP1 EIF3G ETFBKMT FAT1 HERC3 ITM2A IVNS1ABP KAT2B KIF3A LAMTOR1 MITD1 MNAT1 MRPL24 NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR2G PPP2R3C RAB5A RAB9A RBM33 RLF RNF125 RNF20 SMARCB1 SMIM3 STK38 TAX1BP1 TMEM167A UBE2B UBE2N UNK WDR35 WRNIP1 ZC4H2 ZFP36L2 ZNF652
Entrez ID		79868	9830
HPRD ID		06542	05948
Ensembl ID		ENSG00000101901	ENSG00000106785
Uniprot IDs		A0A087WT15 A0A087WX43 Q9NP73	A0A024R165 Q14142
PDB IDs
Enriched GO Terms of Interacting Partners?
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