TRIM14 and ATP2A2

Number of citations of the paper that reports this interaction (PubMedID 29053956)
17

Data Source:
BioGRID (two hybrid)

		TRIM14	ATP2A2
Description		tripartite motif containing 14	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane	Cell Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Vesicle Membrane Membrane Sarcoplasmic Reticulum Platelet Dense Tubular Network Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Protein-containing Complex Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm Apical Ectoplasmic Specialization Ribbon Synapse Plasma Membrane Bounded Cell Projection
	Molecular Function	Molecular_function Zinc Ion Binding	Calcium-transporting ATPase Activity Calcium Ion Binding Protein Binding ATP Binding Proton-exporting ATPase Activity, Phosphorylative Mechanism Enzyme Binding Lutropin-choriogonadotropic Hormone Receptor Binding Ion Channel Binding S100 Protein Binding Calcium-transporting ATPase Activity Involved In Regulation Of Cardiac Muscle Cell Membrane Potential
	Biological Process	Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity	Regulation Of The Force Of Heart Contraction Skeletal Muscle Contraction Cellular Calcium Ion Homeostasis ER-nucleus Signaling Pathway Organelle Organization Cell Adhesion Epidermis Development Positive Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Transition Between Fast And Slow Fiber Cardiac Muscle Hypertrophy In Response To Stress Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Response To Lipopolysaccharide T-tubule Organization Ion Transmembrane Transport Cellular Response To Oxidative Stress Cellular Response To Heat Response To Endoplasmic Reticulum Stress Negative Regulation Of Heart Contraction Relaxation Of Cardiac Muscle Sarcoplasmic Reticulum Calcium Ion Transport Calcium Ion Transmembrane Transport Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Negative Regulation Of Receptor Binding Proton Transmembrane Transport Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Calcium Ion Transport From Cytosol To Endoplasmic Reticulum Regulation Of Cardiac Conduction Calcium Ion Import Into Sarcoplasmic Reticulum
Pathways		Interferon gamma signaling	Pre-NOTCH Processing in Golgi Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases
Drugs
Diseases			Acrokeratosis verruciformis Darier disease; Dyskeratosis follicularis
GWAS		Multiple sclerosis ( 31604244)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Glucose homeostasis traits ( 25524916) Protein quantitative trait loci ( 18464913) QT interval ( 24952745) Schizophrenia ( 28991256 25056061 29483656 30285260) Waist circumference ( 28552196)
Interacting Genes		52 interacting genes: ABCF3 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H CENPC CSPP1 EIF3G ETFBKMT FAT1 HERC3 ITM2A IVNS1ABP KAT2B KIF3A LAMTOR1 MITD1 MNAT1 MRPL24 NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR2G PPP2R3C RAB5A RAB9A RBM33 RLF RNF125 RNF20 SMARCB1 SMIM3 STK38 TAX1BP1 TMEM167A UBE2B UBE2N UNK WDR35 WRNIP1 ZC4H2 ZFP36L2 ZNF652	10 interacting genes: BCL2 CAMK2A HGS IRS1 IRS2 MDM2 PLN S100A1 SPP1 TRIM14
Entrez ID		9830	488
HPRD ID		05948	00161
Ensembl ID		ENSG00000106785	ENSG00000174437
Uniprot IDs		A0A024R165 Q14142	A0A0S2Z3L2 P16615
PDB IDs			5ZTF 6JJU
Enriched GO Terms of Interacting Partners?
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