TRIM14 and PPP2R3C

Number of citations of the paper that reports this interaction (PubMedID 29053956)
17

Data Source:
BioGRID (two hybrid)

		TRIM14	PPP2R3C
Description		tripartite motif containing 14	protein phosphatase 2 regulatory subunit B''gamma
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane	Nucleoplasm Golgi Apparatus Centrosome Spindle Cytosol
	Molecular Function	Molecular_function Zinc Ion Binding	Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity	Microtubule Cytoskeleton Organization B Cell Homeostasis Regulation Of Antimicrobial Humoral Response Cortical Cytoskeleton Organization Activation Of Protein Kinase Activity Regulation Of Dephosphorylation T Cell Homeostasis Positive Regulation Of B Cell Differentiation Spleen Development Regulation Of Mitochondrial Depolarization
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)	Atopic dermatitis ( 26482879) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Colorectal carcinoma in primary sclerosing cholangitis ( 28779025) Lymphocyte counts ( 27863252) Monocyte percentage of white cells ( 27863252)
Interacting Genes		52 interacting genes: ABCF3 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H CENPC CSPP1 EIF3G ETFBKMT FAT1 HERC3 ITM2A IVNS1ABP KAT2B KIF3A LAMTOR1 MITD1 MNAT1 MRPL24 NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR2G PPP2R3C RAB5A RAB9A RBM33 RLF RNF125 RNF20 SMARCB1 SMIM3 STK38 TAX1BP1 TMEM167A UBE2B UBE2N UNK WDR35 WRNIP1 ZC4H2 ZFP36L2 ZNF652	8 interacting genes: CCDC33 CMTM5 HSPB1 IKBKB MTNR1A POLR1C RTN3 TRIM14
Entrez ID		9830	55012
HPRD ID		05948	12622
Ensembl ID		ENSG00000106785	ENSG00000092020
Uniprot IDs		A0A024R165 Q14142	Q969Q6
PDB IDs
Enriched GO Terms of Interacting Partners?
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