MATR3 and AIMP2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		MATR3	AIMP2
Description		matrin 3	aminoacyl tRNA synthetase complex interacting multifunctional protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Membrane Nuclear Matrix	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex
	Molecular Function	RNA Binding MRNA Binding Structural Molecule Activity Protein Binding Zinc Ion Binding MiRNA Binding Identical Protein Binding	Protein Binding Molecular Adaptor Activity
	Biological Process	Activation Of Innate Immune Response Heart Valve Development Ventricular Septum Development Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Innate Immune Response	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity
Pathways			Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
GWAS		Body mass index ( 26426971) Metabolite levels ( 23823483)	Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		18 interacting genes: AIMP2 AKTIP CALM1 EGFR ERG GFI1B HNRNPK LMNA PCBP1 PTBP2 RASD1 SNAP23 SNRNP200 SRPK2 TNFRSF21 TRAF6 TTF2 UBE2I	48 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BYSL C19orf57 CEP126 CHD3 DARS1 DARS2 DEAF1 DSN1 EPRS1 EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS1 KDR KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 SMURF2 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT
Entrez ID		9782	7965
HPRD ID		05270	02915
Ensembl ID		ENSG00000015479	ENSG00000106305
Uniprot IDs		A0A0R4J2E8 B3KM87 B4DF66 P43243 Q9H4N1	A0A024QZY1 A8MU58 Q13155
PDB IDs			4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39
Enriched GO Terms of Interacting Partners?
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