MATR3 and PTBP2

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		MATR3	PTBP2
Description		matrin 3	polypyrimidine tract binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Membrane Nuclear Matrix	Nucleus Spliceosomal Complex Growth Cone Neuronal Cell Body
	Molecular Function	RNA Binding MRNA Binding Structural Molecule Activity Protein Binding Zinc Ion Binding MiRNA Binding Identical Protein Binding	RNA Binding MRNA Binding
	Biological Process	Activation Of Innate Immune Response Heart Valve Development Ventricular Septum Development Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Innate Immune Response	MRNA Splice Site Selection Regulation Of Translation Spinal Cord Development Cerebellum Development Negative Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation
Pathways
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
GWAS		Body mass index ( 26426971) Metabolite levels ( 23823483)	Anorexia nervosa ( 31308545) Autism spectrum disorder ( 30804558) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically inactive individuals ( 28448500) Chronotype ( 30696823) Headache ( 29397368) Hip circumference ( 25673412) Number of sexual partners ( 30643258) Reaction time ( 29844566) Regular attendance at a pub or social club ( 29970889) Schizophrenia ( 19571811 22688191) Smoking status (ever vs never smokers) ( 30643258) Trunk fat mass adjusted for trunk lean mass ( 30944420) Waist circumference ( 25673412)
Interacting Genes		18 interacting genes: AIMP2 AKTIP CALM1 EGFR ERG GFI1B HNRNPK LMNA PCBP1 PTBP2 RASD1 SNAP23 SNRNP200 SRPK2 TNFRSF21 TRAF6 TTF2 UBE2I	20 interacting genes: CALCOCO2 EIF5A2 ELAVL1 GBP1 GOLGA2 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PKN2 PUF60 QKI RBM10 RBM4 SNRPA TOM1
Entrez ID		9782	58155
HPRD ID		05270	12233
Ensembl ID		ENSG00000015479	ENSG00000117569
Uniprot IDs		A0A0R4J2E8 B3KM87 B4DF66 P43243 Q9H4N1	B4DSS8 B4DSU5 Q9UKA9
PDB IDs			2CQ1 2MJU 4CQ1
Enriched GO Terms of Interacting Partners?
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