RABEP1 and GGA2

Number of citations of the paper that reports this interaction (PubMedID 10747088)
110

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		RABEP1	GGA2
Description		rabaptin, RAB GTPase binding effector protein 1	golgi associated, gamma adaptin ear containing, ARF binding protein 2
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GO Annotations	Cellular Component	Endosome Early Endosome Endocytic Vesicle Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Recycling Endosome	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin-coated Vesicle Early Endosome Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity	Protein Binding ADP-ribosylation Factor Binding
	Biological Process	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Positive Regulation Of GTPase Activity Membrane Fusion Protein Localization To Ciliary Membrane	Intracellular Protein Transport Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process
Pathways		TBC/RABGAPs	TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases
GWAS		Body mass index ( 28892062 25673413) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)
Interacting Genes		24 interacting genes: AP1G1 AP1G2 ATXN7 CASP3 CCND1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 ITSN2 RAB1A RAB33B RAB4A RAB5A RABGEF1 RGS17 SMURF1 SRPK2 TRIM26 TSC2 UBC YWHAG	34 interacting genes: ADRA2B AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC FBXO7 GGA1 GGA3 GOLGA2 HGS HTT IGF2R LRP3 M6PR MAP3K1 PIN1 RABEP1 RABGEF1 RNF11 SORL1 SORT1 SPG21 STAB1 SYNRG TOLLIP TRIM23 VPS18
Entrez ID		9135	23062
HPRD ID		04684	09347
Ensembl ID		ENSG00000029725	ENSG00000103365
Uniprot IDs		B4DMM4 Q15276	Q9UJY4
PDB IDs		1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U	1MHQ
Enriched GO Terms of Interacting Partners?
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