GGA2 and CA8

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		GGA2	CA8
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 2	carbonic anhydrase 8
Image
GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin-coated Vesicle Early Endosome Membrane	Cytoplasm
	Molecular Function	Protein Binding ADP-ribosylation Factor Binding	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding
	Biological Process	Intracellular Protein Transport Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process	Phosphatidylinositol-mediated Signaling
Pathways		TBC/RABGAPs Amyloid fiber formation
Drugs			Zonisamide
Diseases
GWAS			Blood protein levels ( 30072576) Cardiac hypertrophy ( 21348951) Free thyroxine concentration ( 30367059) Height ( 31562340) Myopia ( 27182965) Obesity-related traits ( 23251661) Parkinson's disease ( 27182965) Response to amphetamines ( 22952603) Schizophrenia ( 28991256 25056061 29483656 30285260) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		34 interacting genes: ADRA2B AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC FBXO7 GGA1 GGA3 GOLGA2 HGS HTT IGF2R LRP3 M6PR MAP3K1 PIN1 RABEP1 RABGEF1 RNF11 SORL1 SORT1 SPG21 STAB1 SYNRG TOLLIP TRIM23 VPS18	12 interacting genes: CRX GGA2 HSD17B14 INTS7 ITPR1 LNX1 LRCH4 MAGED1 RAB34 SPDL1 STAT3 TBX3
Entrez ID		23062	767
HPRD ID		09347	00266
Ensembl ID		ENSG00000103365	ENSG00000178538
Uniprot IDs		Q9UJY4	P35219
PDB IDs		1MHQ	2W2J
Enriched GO Terms of Interacting Partners?
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