GGA2 and SPG21

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GGA2	SPG21
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 2	SPG21 abhydrolase domain containing, maspardin
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin-coated Vesicle Early Endosome Membrane	Golgi Apparatus Cytosol Endosome Membrane Trans-Golgi Network Transport Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding ADP-ribosylation Factor Binding	Protein Binding CD4 Receptor Binding
	Biological Process	Intracellular Protein Transport Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process	Antigen Receptor-mediated Signaling Pathway
Pathways		TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		34 interacting genes: ADRA2B AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC FBXO7 GGA1 GGA3 GOLGA2 HGS HTT IGF2R LRP3 M6PR MAP3K1 PIN1 RABEP1 RABGEF1 RNF11 SORL1 SORT1 SPG21 STAB1 SYNRG TOLLIP TRIM23 VPS18	37 interacting genes: AGTRAP AKIRIN2 ARL6IP1 CCDC102B CCDC33 CD4 CMTM5 CRYAA CTPS2 CUTC DTX2 DTX3L EFHC2 FAM114A1 GGA2 GSK3A IKZF3 INCA1 KRT15 LMNA MID2 MTMR9 PRPS1 RABAC1 REEP6 RTN4 S100B SPRED2 TCF12 TCF4 TFG TRAF1 TRAF2 TRIM23 TRIM54 TRIM9 ZNF263
Entrez ID		23062	51324
HPRD ID		09347	10492
Ensembl ID		ENSG00000103365	ENSG00000090487
Uniprot IDs		Q9UJY4	A0A024R5Y1 Q9NZD8
PDB IDs		1MHQ
Enriched GO Terms of Interacting Partners?
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