RABEP1 and AP1G1

Number of citations of the paper that reports this interaction (PubMedID 12505986)
55

Data Source:
HPRD (in vitro)

		RABEP1	AP1G1
Description		rabaptin, RAB GTPase binding effector protein 1	adaptor related protein complex 1 subunit gamma 1
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GO Annotations	Cellular Component	Endosome Early Endosome Endocytic Vesicle Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Recycling Endosome	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity	Protein Binding Rab GTPase Binding Kinesin Binding GTP-dependent Protein Binding
	Biological Process	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Positive Regulation Of GTPase Activity Membrane Fusion Protein Localization To Ciliary Membrane	Intracellular Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Golgi To Lysosome Transport
Pathways		TBC/RABGAPs	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Body mass index ( 28892062 25673413) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)	General cognitive ability ( 29844566) Post bronchodilator FEV1 ( 26634245) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		24 interacting genes: AP1G1 AP1G2 ATXN7 CASP3 CCND1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 ITSN2 RAB1A RAB33B RAB4A RAB5A RABGEF1 RGS17 SMURF1 SRPK2 TRIM26 TSC2 UBC YWHAG	24 interacting genes: AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CLINT1 CLTC DNER EPS15 KIF13A MAP1A PSEN2 RABEP1 RABGEF1 SPTB SYNRG SYP UBL7 UPF1 ZNF512B
Entrez ID		9135	164
HPRD ID		04684	04637
Ensembl ID		ENSG00000029725	ENSG00000166747
Uniprot IDs		B4DMM4 Q15276	A0A140VJE7 O43747 Q8IY97
PDB IDs		1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U	1IU1
Enriched GO Terms of Interacting Partners?
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