FATE1 and CD79A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FATE1	CD79A
Description		fetal and adult testis expressed 1	CD79a molecule
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondria-associated ER Membrane	Multivesicular Body Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane B Cell Receptor Complex Membrane Raft
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration	Adaptive Immune Response B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway
Pathways			CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Systemising ( 31508503)
Interacting Genes		57 interacting genes: AGTRAP AQP9 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 CCDC70 CD302 CD79A CSF2RA CXCR3 DCTN5 EMD GPR25 INPP5K KASH5 KCNS2 LMNA LNPEP MARCHF2 MARCHF5 MR1 NDUFB11 NRG4 NRSN1 OCLN PIN4 PRRG2 RNF183 RPRM SEC22A SEC22C SEC23B SLC38A1 SLC7A1 SMIM14 SNAP47 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM74 TRAF2 TRAF3IP3 USHBP1 USP20 YIPF2 YIPF4	17 interacting genes: BLK BLNK CD19 CD5 CD79B FANCA FATE1 FCAR FYN HCLS1 IGHM JCHAIN LCK LYN PIGR PTPN6 SYK
Entrez ID		89885	973
HPRD ID		02346	00203
Ensembl ID		ENSG00000147378	ENSG00000105369
Uniprot IDs		Q969F0	P11912
PDB IDs			1CV9
Enriched GO Terms of Interacting Partners?
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