CD79A and PIGR

Number of citations of the paper that reports this interaction (PubMedID 12186846)
5

Data Source:
HPRD (in vivo)

		CD79A	PIGR
Description		CD79a molecule	polymeric immunoglobulin receptor
Image
GO Annotations	Cellular Component	Multivesicular Body Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane B Cell Receptor Complex Membrane Raft	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Azurophil Granule Membrane Receptor Complex Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding	Polymeric Immunoglobulin Receptor Activity
	Biological Process	Adaptive Immune Response B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Epidermal Growth Factor Receptor Signaling Pathway Fc Receptor Signaling Pathway Receptor Clustering Neutrophil Degranulation
Pathways		CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Neutrophil degranulation
Drugs
Diseases		Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS			Blood protein levels ( 30072576 29875488) Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Inflammatory bowel disease ( 23128233) Metabolite levels ( 23823483) Precuneus cortex volume ( 31530798)
Interacting Genes		17 interacting genes: BLK BLNK CD19 CD5 CD79B FANCA FATE1 FCAR FYN HCLS1 IGHM JCHAIN LCK LYN PIGR PTPN6 SYK	4 interacting genes: AP1M1 CCL5 CD79A RAB3B
Entrez ID		973	5284
HPRD ID		00203	01436
Ensembl ID		ENSG00000105369	ENSG00000162896
Uniprot IDs		P11912	P01833
PDB IDs		1CV9	1XED 2OCW 3CHN 3CM9 5D4K
Enriched GO Terms of Interacting Partners?
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