FATE1 and BTN2A2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FATE1	BTN2A2
Description		fetal and adult testis expressed 1	butyrophilin subfamily 2 member A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondria-associated ER Membrane	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration	Regulation Of Cytokine Production Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Regulatory T Cell Differentiation Negative Regulation Of Activated T Cell Proliferation Negative Regulation Of Cytokine Secretion Regulation Of Immune Response T Cell Receptor Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Systemising ( 31508503)	Autism spectrum disorder or schizophrenia ( 28540026) General cognitive ability ( 29844566) Headache ( 29397368) Intelligence (MTAG) ( 29326435) Neurociticism ( 29500382) Schizophrenia ( 19571809)
Interacting Genes		57 interacting genes: AGTRAP AQP9 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 CCDC70 CD302 CD79A CSF2RA CXCR3 DCTN5 EMD GPR25 INPP5K KASH5 KCNS2 LMNA LNPEP MARCHF2 MARCHF5 MR1 NDUFB11 NRG4 NRSN1 OCLN PIN4 PRRG2 RNF183 RPRM SEC22A SEC22C SEC23B SLC38A1 SLC7A1 SMIM14 SNAP47 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM74 TRAF2 TRAF3IP3 USHBP1 USP20 YIPF2 YIPF4	4 interacting genes: CREB3 FATE1 LMNA PSMA3
Entrez ID		89885	10385
HPRD ID		02346	12545
Ensembl ID		ENSG00000147378	ENSG00000124508
Uniprot IDs		Q969F0	A0A024R038 Q8WVV5
PDB IDs
Enriched GO Terms of Interacting Partners?
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