KLF7 and IMPDH2

		KLF7	IMPDH2
Description		Kruppel like factor 7	inosine monophosphate dehydrogenase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Extracellular Region Nucleus Cytoplasm Peroxisomal Membrane Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Coactivator Activity Zinc Ion Binding	Nucleotide Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Axonogenesis Axon Guidance Glucose Homeostasis Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Dendrite Morphogenesis Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Negative Regulation Of Adipose Tissue Development	GMP Biosynthetic Process GTP Biosynthetic Process Circadian Rhythm Purine Ribonucleoside Monophosphate Biosynthetic Process Neutrophil Degranulation Lymphocyte Proliferation Oxidation-reduction Process Retina Development In Camera-type Eye Cellular Response To Interleukin-4
Pathways			Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis
Drugs			NADH Mycophenolate mofetil Ribavirin Mycophenolic acid Mercaptopurine Selenazole-4-Carboxyamide-Adenine Dinucleotide 6-Chloropurine Riboside, 5'-Monophosphate Inosinic Acid VX-148
Diseases
GWAS		Chromosomal aberration frequency (chromatid type) in genotoxic compound exposure ( 31586183) Diastolic blood pressure ( 30224653) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Lachrymal/Salivary gland lesion in type 1 autoimmune pancreatitis ( 25985088) Red blood cell count ( 27863252) Self-rated health ( 27864402) Smoking status (ever vs never smokers) ( 30643258) Urinary albumin excretion (no hypertensive medication) ( 30220432)	Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		3 interacting genes: APP FBXO38 IMPDH2	24 interacting genes: AKT1 ALS2 AMT ANKRD9 APIP APPL1 ATXN2 ATXN7 C1S CEACAM5 CLK1 CPLANE2 DCAF1 DNASE1L3 FBXL7 KLF7 PIAS4 PRMT1 PXMP2 PXN RAD54L2 RBM15B SUMO4 UBQLN4
Entrez ID		8609	3615
HPRD ID		07279	00895
Ensembl ID		ENSG00000118263	ENSG00000178035
Uniprot IDs		A0A024R3X8 O75840	A0A384N6C2 P12268
PDB IDs			1B3O 1NF7 1NFB 6I0M 6I0O
Enriched GO Terms of Interacting Partners?
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