TNIP2 and SMARCD1

Number of citations of the paper that reports this interaction (PubMedID 12753905)
3

Data Source:
HPRD (two hybrid)

		TNIP2	SMARCD1
Description		TNFAIP3 interacting protein 2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Nucleoplasm SWI/SNF Complex Intracellular Membrane-bounded Organelle NpBAF Complex NBAF Complex
	Molecular Function	Protein Binding Protein Kinase Binding Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding	Chromatin Binding Transcription Coactivator Activity Signaling Receptor Binding Protein Binding Molecular Adaptor Activity
	Biological Process	Apoptotic Process Inflammatory Response I-kappaB Kinase/NF-kappaB Signaling Protein Deubiquitination CD40 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Macrophage Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription By RNA Polymerase II Protein Stabilization Positive Regulation Of B Cell Activation Stress-activated MAPK Cascade Interleukin-1-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Negative Regulation Of Endothelial Cell Apoptotic Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Chromatin-mediated Maintenance Of Transcription Cellular Response To Fatty Acid
Pathways		MAP3K8 (TPL2)-dependent MAPK1/3 activation Ovarian tumor domain proteases	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Extrinsic epigenetic age acceleration ( 29374233) Multiple sclerosis ( 31604244)	Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)
Interacting Genes		25 interacting genes: APP CDKN1A CLK1 EP300 FBXO25 FLNA IKBKG MAP3K8 MAPK1 MKNK1 NCOR2 NDUFB9 NFKB1 NFKB2 PSMD9 REL RELA SMARCD1 SMURF1 SRPK2 STK11 TEK TNFAIP3 TSG101 UBC	50 interacting genes: ANKS1A ANP32B APOA5 AR C4BPA CALCOCO2 CCDC85B CDC5L CDX2 CHFR CHN2 CLNK CORO1A EGFL7 ESR1 FBXO7 FEZ1 FOS FUS GATA1 GCC1 HNRNPC HSPB1 IGKC JUN KDM1A KLF1 KMT5B KRT15 KRT18 LDOC1 MED4 MTNR1B NME1 NONO NR1H4 NR3C1 NUCB2 PAICS PCBD1 PGR PRDX1 PRMT6 RIF1 RPS29 TNIP2 TP53 USHBP1 VPS37B YWHAG
Entrez ID		79155	6602
HPRD ID		18207	03438
Ensembl ID		ENSG00000168884	ENSG00000066117
Uniprot IDs		D6RGJ2 Q8NFZ5	Q96GM5
PDB IDs		5H07
Enriched GO Terms of Interacting Partners?
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