SMARCD1 and RIF1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SMARCD1	RIF1
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	replication timing regulatory factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm SWI/SNF Complex Intracellular Membrane-bounded Organelle NpBAF Complex NBAF Complex	Chromosome, Telomeric Region Nuclear Chromatin Condensed Chromosome Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Cytoplasm Plasma Membrane Nuclear Body Nuclear Membrane Site Of Double-strand Break Spindle Midzone
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Signaling Receptor Binding Protein Binding Molecular Adaptor Activity	Protein Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Chromatin-mediated Maintenance Of Transcription Cellular Response To Fatty Acid	Negative Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Double-strand Break Repair Via Nonhomologous End Joining Chromatin Silencing At Telomere Cellular Response To DNA Damage Stimulus Cell Cycle Stem Cell Population Maintenance Telomere Maintenance In Response To DNA Damage Positive Regulation Of Isotype Switching Positive Regulation Of Histone H3-K9 Methylation Cellular Response To Leukemia Inhibitory Factor Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	Lung cancer ( 23143601) Metabolite levels ( 23823483)
Interacting Genes		50 interacting genes: ANKS1A ANP32B APOA5 AR C4BPA CALCOCO2 CCDC85B CDC5L CDX2 CHFR CHN2 CLNK CORO1A EGFL7 ESR1 FBXO7 FEZ1 FOS FUS GATA1 GCC1 HNRNPC HSPB1 IGKC JUN KDM1A KLF1 KMT5B KRT15 KRT18 LDOC1 MED4 MTNR1B NME1 NONO NR1H4 NR3C1 NUCB2 PAICS PCBD1 PGR PRDX1 PRMT6 RIF1 RPS29 TNIP2 TP53 USHBP1 VPS37B YWHAG	19 interacting genes: BRD7 CEP126 CHD3 DEFB1 FEZ1 GIT1 GNE GRB2 HAP1 LINC00839 NSG2 PABPC4 PIAS4 POT1 PPP1CA PPP1CC SETDB1 SMARCD1 TERF2IP
Entrez ID		6602	55183
HPRD ID		03438	10603
Ensembl ID		ENSG00000066117	ENSG00000080345
Uniprot IDs		Q96GM5	Q5UIP0
PDB IDs
Enriched GO Terms of Interacting Partners?
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