SMARCD1 and PAICS

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SMARCD1	PAICS
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm SWI/SNF Complex Intracellular Membrane-bounded Organelle NpBAF Complex NBAF Complex	Cytoplasm Cytosol Membrane Extracellular Exosome
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Signaling Receptor Binding Protein Binding Molecular Adaptor Activity	Phosphoribosylaminoimidazole Carboxylase Activity Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity Protein Binding ATP Binding Identical Protein Binding 5-amino-4-imidazole Carboxylate Lyase Activity Cadherin Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Chromatin-mediated Maintenance Of Transcription Cellular Response To Fatty Acid	'de Novo' IMP Biosynthetic Process Purine Nucleobase Biosynthetic Process Purine Ribonucleoside Monophosphate Biosynthetic Process
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	Purine ribonucleoside monophosphate biosynthesis
Drugs			L-Aspartic Acid
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)
Interacting Genes		50 interacting genes: ANKS1A ANP32B APOA5 AR C4BPA CALCOCO2 CCDC85B CDC5L CDX2 CHFR CHN2 CLNK CORO1A EGFL7 ESR1 FBXO7 FEZ1 FOS FUS GATA1 GCC1 HNRNPC HSPB1 IGKC JUN KDM1A KLF1 KMT5B KRT15 KRT18 LDOC1 MED4 MTNR1B NME1 NONO NR1H4 NR3C1 NUCB2 PAICS PCBD1 PGR PRDX1 PRMT6 RIF1 RPS29 TNIP2 TP53 USHBP1 VPS37B YWHAG	11 interacting genes: CEP76 CHD3 FXR2 L3MBTL2 LNX1 MOB4 NIF3L1 NUDT18 PRKAG1 SMARCD1 TERF1
Entrez ID		6602	10606
HPRD ID		03438	01401
Ensembl ID		ENSG00000066117	ENSG00000128050
Uniprot IDs		Q96GM5	P22234
PDB IDs			2H31
Enriched GO Terms of Interacting Partners?
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