SMARCD1 and CHN2

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		SMARCD1	CHN2
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	chimerin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm SWI/SNF Complex Intracellular Membrane-bounded Organelle NpBAF Complex NBAF Complex	Cytosol Membrane Synapse
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Signaling Receptor Binding Protein Binding Molecular Adaptor Activity	SH3/SH2 Adaptor Activity GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Chromatin-mediated Maintenance Of Transcription Cellular Response To Fatty Acid	Positive Regulation Of Signal Transduction Intracellular Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	Rho GTPase cycle
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	Circulating leptin levels in high cardiovascular risk ( 31766143) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Facial emotion recognition ( 28608620) Facial emotion recognition (angry faces) ( 28608620) Facial emotion recognition (sad faces) ( 28608620) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Loneliness (linear analysis) ( 27629369) Methadone dose in opioid dependence ( 28115739) Obesity-related traits ( 23251661) Psychosis (atypical) ( 24132900) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		50 interacting genes: ANKS1A ANP32B APOA5 AR C4BPA CALCOCO2 CCDC85B CDC5L CDX2 CHFR CHN2 CLNK CORO1A EGFL7 ESR1 FBXO7 FEZ1 FOS FUS GATA1 GCC1 HNRNPC HSPB1 IGKC JUN KDM1A KLF1 KMT5B KRT15 KRT18 LDOC1 MED4 MTNR1B NME1 NONO NR1H4 NR3C1 NUCB2 PAICS PCBD1 PGR PRDX1 PRMT6 RIF1 RPS29 TNIP2 TP53 USHBP1 VPS37B YWHAG	9 interacting genes: BAG6 ERBB3 RAC1 RACGAP1 RANBP3 RB1 SMARCD1 TGFBR1 TP53RK
Entrez ID		6602	1124
HPRD ID		03438	04173
Ensembl ID		ENSG00000066117	ENSG00000106069
Uniprot IDs		Q96GM5	A0A2X0TVW3 B3VCF4 B3VCF5 B3VCF6 B3VCF9 B7Z1V0 B7Z1W9 B7Z215 B7Z232 P52757
PDB IDs			1XA6
Enriched GO Terms of Interacting Partners?
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