SMARCD1 and KLF1

Number of citations of the paper that reports this interaction (PubMedID 11018012)
80

Data Source:
BioGRID (pull down)

		SMARCD1	KLF1
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	Kruppel like factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm SWI/SNF Complex Intracellular Membrane-bounded Organelle NpBAF Complex NBAF Complex	Nuclear Chromatin Nucleus Nucleoplasm
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Signaling Receptor Binding Protein Binding Molecular Adaptor Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Chromatin-mediated Maintenance Of Transcription Cellular Response To Fatty Acid	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Erythrocyte Differentiation Positive Regulation Of Transcription, DNA-templated Maternal Process Involved In Female Pregnancy Cellular Response To Peptide
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases			Congenital dyserythropoietic anemias (CDAs)
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	Clozapine-induced agranulocytosis ( 25187353) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Mean corpuscular volume ( 29403010 27863252) Red blood cell count ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		50 interacting genes: ANKS1A ANP32B APOA5 AR C4BPA CALCOCO2 CCDC85B CDC5L CDX2 CHFR CHN2 CLNK CORO1A EGFL7 ESR1 FBXO7 FEZ1 FOS FUS GATA1 GCC1 HNRNPC HSPB1 IGKC JUN KDM1A KLF1 KMT5B KRT15 KRT18 LDOC1 MED4 MTNR1B NME1 NONO NR1H4 NR3C1 NUCB2 PAICS PCBD1 PGR PRDX1 PRMT6 RIF1 RPS29 TNIP2 TP53 USHBP1 VPS37B YWHAG	14 interacting genes: ARID1A CREBBP CSNK2A1 CSNK2A2 EP300 FLI1 HDAC1 PRKACA SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCE1
Entrez ID		6602	10661
HPRD ID		03438	07197
Ensembl ID		ENSG00000066117	ENSG00000105610
Uniprot IDs		Q96GM5	Q13351
PDB IDs			2L2I 2MBH 2N23
Enriched GO Terms of Interacting Partners?
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