PAICS and NUDT18

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PAICS	NUDT18
Description		phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase	nudix hydrolase 18
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Extracellular Exosome	Cytosol
	Molecular Function	Phosphoribosylaminoimidazole Carboxylase Activity Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity Protein Binding ATP Binding Identical Protein Binding 5-amino-4-imidazole Carboxylate Lyase Activity Cadherin Binding	Magnesium Ion Binding Protein Binding 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity
	Biological Process	'de Novo' IMP Biosynthetic Process Purine Nucleobase Biosynthetic Process Purine Ribonucleoside Monophosphate Biosynthetic Process	Nucleobase-containing Small Molecule Catabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process
Pathways		Purine ribonucleoside monophosphate biosynthesis
Drugs		L-Aspartic Acid
Diseases
GWAS
Interacting Genes		11 interacting genes: CEP76 CHD3 FXR2 L3MBTL2 LNX1 MOB4 NIF3L1 NUDT18 PRKAG1 SMARCD1 TERF1	34 interacting genes: APIP CAVIN2 COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1
Entrez ID		10606	79873
HPRD ID		01401	07992
Ensembl ID		ENSG00000128050	ENSG00000275074
Uniprot IDs		P22234	Q6ZVK8
PDB IDs		2H31	3GG6 4HVY
Enriched GO Terms of Interacting Partners?
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